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Jiangtao YAN, Rutai HUI, Daowen WANG
《医学前沿(英文)》 2009年 第3卷 第1期 页码 30-35 doi: 10.1007/s11684-009-0005-x
Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:
null
《医学前沿(英文)》 2018年 第12卷 第3期 页码 319-323 doi: 10.1007/s11684-017-0553-4
Antithrombin and protein C are two crucial members in the anticoagulant system and play important roles in hemostasis. Mutations in and lead to deficiency or dysfunction of the two proteins, which could result in venous thromboembolism (VTE). Here, we report a Chinese 22-year-old young man who developed recurrent and serious VTE in cerebral veins, visceral veins, and deep veins of the lower extremity. Laboratory tests and direct sequencing of and were conducted for the patient and his family members. Coagulation tests revealed that the patient presented type I antithrombin deficiency combined with decreased protein C activity resulting from a small insertion mutation c.848_849insGATGT in and a short deletion variant c.572_574delAGA in . This combination of the two mutations was absent in 400 healthy subjects each from southern and northern China. Then, we summarized all the mutations of the and gene reported in the Chinese Han population. This study demonstrates that the combination of antithrombin deficiency and decreased protein C activity can result in severe VTE and that the coexistence of different genetic factors may increase the risk of VTE.
关键词: antithrombin deficiency protein C activity mutation variant venous thromboembolism anticoagulants
The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases
null
《医学前沿(英文)》 2011年 第5卷 第1期 页码 70-76 doi: 10.1007/s11684-011-0119-9
Protein kinase C epsilon (PKC ?) is one of major isoforms in novel PKC family. Although it has been extensively characterized in the past decade, the role of PKC ? in neuron is still not well understood. Advances in molecular biology have now removed significant barriers to the direct investigation of PKC ? functions in vivo, and PKC ? has been increasingly implicated in the neural biological functions and associated neurogenic diseases. Recent studies have provided important insights into the influence of PKC ? on cortical processing at both the single cell level and network level. These studies provide compelling evidence that PKC ? could regulate distinct aspects of neural signal transduction and suggest that the coordinated actions of a number of molecular signals contribute to the specification and differentiation of PKC ? signal pathway in the developing brain.
关键词: protein kinase C ? signal transduction neurogenic disease
C. LAYEK
《化学科学与工程前沿(英文)》 2011年 第5卷 第4期 页码 471-476 doi: 10.1007/s11705-011-1130-z
关键词: slip flow MHD boundary layer reactive solute diffusion flat plate suction/injection
Targeting “undruggable” c-Myc protein by synthetic lethality
Chen Wang, Hui Fang, Jiawei Zhang, Ying Gu
《医学前沿(英文)》 2021年 第15卷 第4期 页码 541-550 doi: 10.1007/s11684-020-0780-y
关键词: synthetic lethality undruggable transcription factor c-Myc
immune mapped protein 1 (NcIMP1) is a novel vaccine candidate against neosporosis
Xia CUI,Daoyu YANG,Tao LEI,Hui WANG,Pan HAO,Qun LIU
《农业科学与工程前沿(英文)》 2015年 第2卷 第1期 页码 66-72 doi: 10.15302/J-FASE-2015047
关键词: Neospora caninum immune mapped protein 1 (IMP1) vaccine candidate BALB/c mice
Xiaowei ZHANG,Qinyan YUE,Dongting YUE,Baoyu GAO,Xiaojuan WANG
《环境科学与工程前沿(英文)》 2015年 第9卷 第3期 页码 402-410 doi: 10.1007/s11783-014-0659-8
关键词: Fe0/C/Clay ceramics micro-electrolysis Acid Red 73 Reactive Blue 4 synthetic wastewater
Design and optimization of reactive distillation: a review
《化学科学与工程前沿(英文)》 2022年 第16卷 第6期 页码 799-818 doi: 10.1007/s11705-021-2128-9
关键词: reactive distillation process intensification design method reactive phase diagram optimization algorithm
《环境科学与工程前沿(英文)》 2022年 第16卷 第12期 doi: 10.1007/s11783-022-1591-y
● A novel PRB configuration based on passive convergent flow effect was proposed.
关键词: Passive convergence-permeable reactive barrier (PC-PRB) Permeable reactive barrier configuration Numerical simulation Hydraulic performance evaluation Sensitivity analysis
Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction
Hong LI,Ziding ZHANG
《农业科学与工程前沿(英文)》 2016年 第3卷 第2期 页码 102-112 doi: 10.15302/J-FASE-2016100
关键词: plant–pathogen interactions systems biology omics plant immunity protein–protein interaction network
《环境科学与工程前沿(英文)》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1372-4
• The MCNZVI is prepared as an interesting material for PS activation.
关键词: MCNZVI Core-shell structure Reactive Black 5 Persulfate Mechanism
GASEOUS REACTIVE NITROGEN LOSSES FROM ORCHARDS, VEGETABLES AND TEA PLANTATIONS
《农业科学与工程前沿(英文)》 2023年 第10卷 第2期 页码 155-166 doi: 10.15302/J-FASE-2022477
● Gaseous N emissions from orchards, vegetables and tea plantations (OVT) are reviewed.
关键词: fruit greenhouse gas green development fertilizer management climate change
Tuned reactive power dispatch through modified differential evolution technique
S. BISWAS (RAHA), N. CHAKRABORTY
《能源前沿(英文)》 2012年 第6卷 第2期 页码 138-147 doi: 10.1007/s11708-012-0188-8
关键词: reactive power dispatch (RPD) modified differential evolution (MDE) differential evolution algorithm with localizations around the best vector (DELB)
Yi ZHAO,Tianxiang GUO,Zili ZANG
《环境科学与工程前沿(英文)》 2015年 第9卷 第2期 页码 222-229 doi: 10.1007/s11783-014-0636-2
关键词: “Oxygen-enriched” highly reactive absorbent Surface characteristics Flue gas circulating fluidized bed Simultaneous desulfurization and denitrification
Hong SUN,Min SUN,Yaobin ZHANG,Xie QUAN
《环境科学与工程前沿(英文)》 2015年 第9卷 第4期 页码 591-595 doi: 10.1007/s11783-014-0694-5
关键词: catalytic ozonation reactive red X-3B ceramic honeycomb hydroxyl radical (OH·)
标题 作者 时间 类型 操作
Elevated C-reactive protein levels predict worsening prognosis in Chinese patients with first-onset stroke
Jiangtao YAN, Rutai HUI, Daowen WANG
期刊论文
Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:
null
期刊论文
The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases
null
期刊论文
Magnetohydrodynamic slip flow and diffusion of a reactive solute past a permeable flat plate with suction
C. LAYEK
期刊论文
Targeting “undruggable” c-Myc protein by synthetic lethality
Chen Wang, Hui Fang, Jiawei Zhang, Ying Gu
期刊论文
immune mapped protein 1 (NcIMP1) is a novel vaccine candidate against neosporosis
Xia CUI,Daoyu YANG,Tao LEI,Hui WANG,Pan HAO,Qun LIU
期刊论文
Passive convergence-permeable reactive barrier (PC-PRB): An effective configuration to enhance hydraulic
期刊论文
Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction
Hong LI,Ziding ZHANG
期刊论文
Preparation of nZVI embedded modified mesoporous carbon for catalytic persulfate to degradation of reactive
期刊论文
Tuned reactive power dispatch through modified differential evolution technique
S. BISWAS (RAHA), N. CHAKRABORTY
期刊论文
Activity and characteristics of “Oxygen-enriched” highly reactive absorbent for simultaneous flue gas
Yi ZHAO,Tianxiang GUO,Zili ZANG
期刊论文